The fall-out from the merger of brewing giants Anheuser-Busch and InBev has begun, with the combined company to axe more than a thousand jobs in the US in a bid to cut costs.

The combined group, which officially tied the knot last month on its $52bn merger, is cutting 1,400 staff from its US brewing business, with its operations in St Louis set to bear the brunt of the lay-offs.

The tie-up between the brewers of Budweiser and Stella Artois created the world’s largest brewing group, with an estimated 25% of the global market.

Meanwhile, rival brewing giant SABMiller has moved to strengthen its commitment to sourcing local ingredients.

The brewer of Peroni and Grolsch has said it will buy  raw materials from an extra 15,000 small farmers in developing countries in Latin America, Africa and India.