The wholesaler launched in the UK in May 1971, and is kicking off its anniversary promotions on 9 March with a 'Drive Away Giveaway'. Customers will get the chance to win a Nissan NV200 van by entering a date from the past 40 years on Makro's website.
Two 'Spend and Save' loyalty promotions are also planned. The first, which will run next month, will offer savings on tableware, with a second planned for the autumn.
In-store events and sampling will also be held as well as a Ruby Ball for hotel, restaurant and catering customers.
"Since opening in 1971, our extensive range and everyday low prices have seen Makro grow to one of the UK's leading wholesalers," said MD Hannes Floto. "We are dedicating our anniversary celebrations to our customers."