Like-for-like food sales for the 13 weeks to 29 December fell 1.5%, with UK like-for-like sales down 2.2% and general merchandise down 3.2%.
The fall wiped more than £1.7bn off the value of the company amid concern M&S would fail to hit full-year pre-tax profit figures above £1bn.
Analysts also questioned whether M&S' performance would prompt the Bank of England to lower interest rates today.
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