The Midlands-based company sells and distributes pharmaceuticals, toiletries, household goods and perfume from its main depot in Blackheath, Birmingham.
Three Pears said it had invested a five-figure sum in the online service, which will be updated daily to show how much stock is available.Retailers can register and start placing orders within 24 hours, it added.
Smaller orders are collected but delivery is offered for bulk purchases.
The global nature of the site could significantly grow Three Pears' database of 5,000 customers, claimed chairman Ed Dunn. "Although we already have customers across the UK and overseas, the online facility will allow even more to buy from further afield."
Three Pears, which has a turnover of £20m and was set up in 1973, was targeting sales on the Continent and the Middle East, he added.