The Waste & Resources Action Programme (Wrap), the government-funded organisation responsible for cutting packaging waste, is axing 31 jobs.
Wrap, which has previously received £70.7m in funding, has been told to make savings of 25% and has made the redundancy announcement ahead of a new budget due to be published in the spring.
The organisation is working on a new business plan and job cuts will be made from areas of low priority, although Wrap would not reveal further details.
No senior posts are expected to be axed.
However, Wrap is offsetting the redundancies by creating 18 new posts in high-priority areas.
The cuts coincide with a wider cost-cutting exercise at Defra, which recently appealed for 300 of its staff to take voluntary redundancy.