The retailer, which is owned by US chain Whole Foods Market, said that the store on Old Street had shut because the landlord of the site was redeveloping the property and its plans did not include Fresh & Wild or Whole Foods Market.
A spokeswoman for Whole Foods Market said the closure was a one-off. "We do not have any plans to close any other Fresh & Wild locations," she said.
Staff at the store will be offered the opportunity to continue employment at Fresh & Wild's five other branches in London. The company also has an outlet in Bristol. "We have enjoyed being part of the neighbourhood for 26 years and appreciate our shoppers who have been loyal patrons," the spokeswoman added.
Whole Foods Market is opening its first UK store on Kensington High Street, London, next spring. The company is currently working to secure sites for further branches.