Set in Rome, the ad focuses on the brand's Italian heritage and aims to show the appeal of the drink to cosmopolitan' ladies after a long day.
It also drives home the message about mixing the drink to consumers who will see Martini Rosso being consumed with cranberry juice.
Martini says it has opted for prime time slots to broadcast the commercial, which starts at the beginning of November.
Caroline Herbert, marketing manager for Martini vermouth, said: "The brand is one of the UK's favourites at Christmas, so this will really help drive sales. It also follows an extensive consumer sampling campaign which ran throughout the summer reinforcing Martini's versatility to approximately 600,000 people.
"The advert brings to life the essence of Martini as a relaxed drink to our target audience of women."