The 4.5% abv Glasgow Special Whyte & McKay Blended Scotch Whisky & Cola (rsp: £1.70) launches this week.
It marks the first time the brand has been used in a pre-mixed drink, and follows Diageo's launch of Smirnoff & Cola in February.
"Having whisky in a ready-mixed format means that consumers who wish to only have one drink can do so without having to open a large bottle of cola, which may then go flat," said Whyte & Mackay off-trade sales director John Bradbury.
The product would bring new consumers to the whisky category, he added.
The company launched Jura and Glayva into 35cl bottles at the end of last month.