It takes a lot to get booed at the Paralympics. But George Osborne managed it last night as he handed out medals for the Men’s T38 400m.

Despite that resounding verdict, Osborne went to sleep in Number 11 knowing his job wasn’t on the line in today’s Cabinet reshuffle. Andrew Lansley, on the other hand, may have suspected his number was up.

The health secretary was the most eye-catching casualty in what was originally trailed as the usual rearranging of deckchairs, rather than something more seismic. His sacking completes a rollercoaster week for Lansley, who was so recently celebrating a major victory on traffic light labelling. It could also have major repercussions for the trade.

The arrival of Jeremy Hunt, an arch Cameron loyalist, could signal a greater appetite for regulation in the Department of Health. Certainly Cameron himself has shown an eagerness for the big stick that Lansley - setting aside his declaration of war on tobacco - broadly lacked, preferring to build consensus via his much-maligned Responsibility Deal.

And conspiracy theorists may suggest we now know the real reason why the government’s inquiry into minimum pricing on alcohol - humiliatingly imposed on Lansley - was delayed until the autumn.

We’ll be taking a closer look at Lansley’s legacy - and the implications of Hunt’s arrival - in this weekend’s edition of The Grocer.

Meanwhile, Caroline Spelman also got the boot today, replaced at Defra by former Northern Ireland secretary Owen Paterson. Her departure feels like more of a footnote.

“It’s a credit to the impact Caroline Spelman has made in 2 years in Cabinet that most of lobby are spelling her name ‘Spellman’,” tweeted Matt Chorley of the Independent on Sunday.

And the editor of BusinessGreen.com added: “Must admit I feel a bit sorry for Spelman. Screw up a little bit (forests etc) you’re gone. Screw up massively (economy etc) you’re safe.”

At time of writing, rumours were swirling that farming minister Jim Paice could also be on his way, with Lib Dem David Heath touted as a replacement. Defra, for now at least, is keeping mum.